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However, complete discontinuation typically results in weight regain, making CagriSema a long-term commitment requiring indefinite maintenance dosing

Overall, while NP-based approaches show strong potential for the diagnosis and treatment of autoimmune disease, further work is required to confirm clinical safety and effectiveness, as many studies remain at the animal-model stage

While current treatments delay the progression of DCM to some extent, their effectiveness and safety remain limited

NADPH not only drives ATP release through coupling with OXPHOS but also maintains the GSH cycle across various metabolic pathways, thus counteracting mitochondrial lipid peroxidation and reducing susceptibility to ferroptosis (51)